BDBM554430 US11332473, Compound 1.249

SMILES CC(C)n1n(-c2ccc(F)c(n2)C(C)(C)O)c2nc(Nc3ccc4CNCCc4c3)ncc2c1=O

InChI Key InChIKey=KOPURAIBHTWXCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554430   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM554430(US11332473, Compound 1.249)
Affinity DataIC50: 16nMAssay Description:WEE1: IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
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LigandPNGBDBM554430(US11332473, Compound 1.249)
Affinity DataIC50: 2.01E+4nMAssay Description:PKMYT1: Inhibition of PKMYT1 kinase activity by test compounds was measured by the HotSpot Kinase Assay at Reaction Biology Corporation (Malvern, Pa....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent