BDBM554413 US11332473, Compound 1.63

SMILES CCn1n(-c2ccnc(c2)C2(CC2)C#N)c2nc(Nc3ccc4c(CCNC4(C)C)c3)ncc2c1=O

InChI Key InChIKey=JVPPSQZUAYRQHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554413   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM554413(US11332473, Compound 1.63)
Affinity DataIC50: 18nMAssay Description:WEE1: IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent