BDBM554181 (1-(((2S,4R,5R)-5-(6-chloro-4- (cyclopentylamino)-1H-pyrazolo[3,4- d]pyrimidin-1-yl)-4-hydroxytetrahydrofuran-2- yl)methoxy)-2-hydroxyethyl)phosphonic acid::US11325938, Ex 40

SMILES OCC(OC[C@@H]1C[C@@H](O)[C@@H](O1)n1ncc2c(NC3CCCC3)nc(Cl)nc12)P(O)(O)=O

InChI Key InChIKey=MAOSDASXTZSNSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554181   

Target5'-nucleotidase(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM554181(US11325938, Ex 40 | (1-(((2S,4R,5R)-5-(6-chloro-4-...)
Affinity DataIC50: 100nMAssay Description:Assay Reaction ConditionsAssay Volume: 70 μlReaction Volume: 50 μlCD73: 0.3208 nMAMP: 15 μMAssay Buffer: 25 mM Tris-HCL, pH 7.4, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent