BDBM554176 ((((2R,3S,4R,5R)-5-(6-chloro-4- (cyclopentylamino)-1H-pyrazolo[3,4- d]pyrimidin-1-yl)-3,4- dihydroxytetrahydrofuran-2-yl)methoxy)(1H- tetrazol-5-yl)methyl)phosphonic acid::US11325938, Ex 35

SMILES O[C@@H]1[C@@H](COC(c2nnn[nH]2)P(O)(O)=O)O[C@H]([C@@H]1O)n1ncc2c(NC3CCCC3)nc(Cl)nc12

InChI Key InChIKey=FXDOSQWZMWBRDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554176   

Target5'-nucleotidase(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM554176(US11325938, Ex 35 | ((((2R,3S,4R,5R)-5-(6-chloro-4...)
Affinity DataIC50: 100nMAssay Description:Assay Reaction ConditionsAssay Volume: 70 μlReaction Volume: 50 μlCD73: 0.3208 nMAMP: 15 μMAssay Buffer: 25 mM Tris-HCL, pH 7.4, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent