BDBM554169 US11332473, Compound 1.2

SMILES CC(C)(F)c1nc(ccc1F)-n1n(C2CC2)c(=O)c2cnc(Nc3ccc4CNCCc4c3)nc12

InChI Key InChIKey=PEFHEJYZHSANJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554169   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM554169(US11332473, Compound 1.2)
Affinity DataIC50: 36nMAssay Description:WEE1: IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
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LigandPNGBDBM554169(US11332473, Compound 1.2)
Affinity DataIC50: 1.02E+4nMAssay Description:PKMYT1: Inhibition of PKMYT1 kinase activity by test compounds was measured by the HotSpot Kinase Assay at Reaction Biology Corporation (Malvern, Pa....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent