BDBM554116 US11325921, Example 6

SMILES [H][C@]12CC[C@]([H])(N[C@@H]1C(=O)N1CC3(C1)CN(C3)c1c(cnc3sc(CC(F)(F)F)cc13)C(F)(F)F)[C@@H](O)C2

InChI Key InChIKey=SGSKCUULBFTJTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554116   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM554116(US11325921, Example 6)
Affinity DataIC50: 27.3nMAssay Description:Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
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