BDBM553877 US11325905, Compound A19B4C10

SMILES NCc1ccc(cc1)N1C(=O)C2C=CC([C@@H](O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc3ccc(cc3)N(=O)=O)[C@@H]2C1=O

InChI Key InChIKey=QJXVVBICJFYXRR-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 553877   

TargetBifunctional polynucleotide phosphatase/kinase(Human)
University of Alberta

US Patent
LigandPNGBDBM553877(US11325905, Compound A19B4C10)
Affinity DataKd:  105nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetBifunctional polynucleotide phosphatase/kinase(Human)
University of Alberta

US Patent
LigandPNGBDBM553877(US11325905, Compound A19B4C10)
Affinity DataIC50: 1.31E+4nMAssay Description:Kd values were measured by steady-state fluorescence spectroscopy, by following protein tryptophan fluorescence quenching as a function of ligand con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent