BDBM553786 US11319304, Compound 116::US11319304, Compound 123

SMILES Nc1cccnc1C(=O)Nc1ccc2c(OCC3COCCO3)nccc2c1

InChI Key InChIKey=NVNWWEUGDDAVSD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 553786   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM553786(US11319304, Compound 123 | US11319304, Compound 11...)
Affinity DataEC50:  63.7nMAssay Description:For human mGluR4 assays, a fluorescence baseline was established for 3-5 seconds, the disclosed compounds were then added to the cells, and the respo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM553786(US11319304, Compound 123 | US11319304, Compound 11...)
Affinity DataEC50:  63.7nMAssay Description:For human mGluR4 assays, a fluorescence baseline was established for 3-5 seconds, the disclosed compounds were then added to the cells, and the respo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent