BDBM553516 US11319299, Example 601::propan-2-yl 5-[2-fluoro- 5-[[6-oxo-4-(trifluoromethyl)- 1H-pyridine-3-carbonyl] amino]-4-[rac-(3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]-3,6-dihydro- 2H-pyridine-1-carboxylate

SMILES CC(C)OC(=O)N1CCC=C(C1)c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1

InChI Key InChIKey=CQBAJGDAFYIFKN-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553516   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM553516(propan-2-yl 5-[2-fluoro- 5-[[6-oxo-4-(trifluoromet...)
Affinity DataKd:  0.271nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent