BDBM553339 N-[4-fluoro-5-[1-[5- (hydroxymethyl)pyrimidin-2-yl]- 3,6-dihydro-2H-pyridin-5-yl]-2- [rac-(3R,5S)-3,4,5- trimethylpiperazin-1-yl)phenyl]- 6-oxo-4-(trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 413

SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCCN(C1)c1ncc(CO)cn1

InChI Key InChIKey=BEXDKQCDSQKQQE-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553339   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM553339(N-[4-fluoro-5-[1-[5- (hydroxymethyl)pyrimidin-2-yl...)
Affinity DataKd:  0.302nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent