BDBM553291 N-[4-fluoro-5-[1-(6- methoxypyrimidin-4-yl)- 3,6-dihydro-2H-pyridin- 5-yl]-2-[rac-(3R,5S)- 3,4,5-trimethylpiperazin- 1-yl]phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 365

SMILES COc1cc(ncn1)N1CCC=C(C1)c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1

InChI Key InChIKey=QKXONJSRJGEGKU-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553291   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM553291(N-[4-fluoro-5-[1-(6- methoxypyrimidin-4-yl)- 3,6-d...)
Affinity DataKd:  0.246nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent