BDBM552835 (R)-7-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl-6-d)thiazol-4-yl)phenyl)-6, 7-dihydro-5H-pyrrolo[1 .2-a]imidazol-7-ol. .::WO2022104348, Example 62::WO2022104348, Example 63

SMILES O[C@]1(CCn2ccnc12)c1cccc(c1)-c1csc(n1)-c1c[nH]c2nccnc12

InChI Key InChIKey=CORIXJQXOPQMJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552835   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552835(WO2022104348, Example 63 | (R)-7-(3-(2-(5H-Pyrrolo...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552835(WO2022104348, Example 63 | (R)-7-(3-(2-(5H-Pyrrolo...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348