BDBM552832 (R)-4-(3-(4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol-2-yl)phenyl)-5,6-dihydro- 4H-cyclopenta[d]thiazol-4-ol.::WO2022104348, Example 59

SMILES O[C@]1(CCc2scnc12)c1cccc(c1)-c1nc(cs1)-c1c[nH]c2nccnc12

InChI Key InChIKey=VSSVFTCWPQVRCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552832   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552832((R)-4-(3-(4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348