BDBM552731 (2S, 4R)-N-((S)-l-(2'-chloro-[l,r-biphenyl]-4-yl)ethyl)-l-((S)-2-(4-cyclopropyl-lH-l,2,3-triazol-l-yl)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide ( Compound 54)::WO2022103411, Compound 54::WO2022103411, Example S46

SMILES C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](n1cc(nn1)C1CC1)C(C)(C)C)c1ccc(cc1)-c1ccccc1Cl

InChI Key InChIKey=RQQIYJWFXPPPSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552731   

LigandPNGBDBM552731(WO2022103411, Compound 54 | (2S, 4R)-N-((S)-l-(2'-...)
Affinity DataIC50: 10nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022103411