BDBM552727 (2S,4R)-l-((S)-2-(4-cyclopropyl-lH-l,2,3-triazol-l-yl)-3,3-climethylbutanoyl)-N-((R)-l-(2'-fluoro-[ l,r-biphenyl -4-yl)ethyl)-4-hyclroxypyrrolidine-2-carboxamide (Compound 48)::WO2022103411, Compound 48::WO2022103411, Example S42

SMILES C[C@@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](n1cc(nn1)C1CC1)C(C)(C)C)c1ccc(cc1)-c1ccccc1F

InChI Key InChIKey=ZFCNGNWGQZFKMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552727   

LigandPNGBDBM552727(WO2022103411, Compound 48 | (2S,4R)-l-((S)-2-(4-cy...)
Affinity DataIC50: 1.10E+3nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022103411