BDBM552711 (2S,4R)-l-((S)-3,3-dimethyl-2-(4-(l-methylcyclopropyl)-lH-l,2,3-triazol-l-yl)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (Compound 29)::WO2022103411, Example S29

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](n2cc(nn2)C2(C)CC2)C(C)(C)C)cc1

InChI Key InChIKey=JBTOFOFMEKQDIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552711   

LigandPNGBDBM552711((2S,4R)-l-((S)-3,3-dimethyl-2-(4-(l-methylcyclopro...)
Affinity DataIC50: 10nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022103411