BDBM552705 (2S,4R)-l-((S)-2-(4-cyclopropyl-lH-l ,2,3-triazol- 1 -yl)-3,3-dimethylpentanoyl)-4-hydroxy-N-( ( S )-l-(4-( 4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide ( Compound 21 )::WO2022103411, Example S21

SMILES CCC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(cc1)-c1scnc1C)n1cc(nn1)C1CC1

InChI Key InChIKey=WJBFFPMKJCJAHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552705   

LigandPNGBDBM552705((2S,4R)-l-((S)-2-(4-cyclopropyl-lH-l ,2,3-triazol-...)
Affinity DataIC50: 5nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022103411