BDBM552700 WO2022103411, Example S16::l-((S)-l-((2S,4R)-2-(((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-oxopropan-2-yl)carbamoyl)-4-hydroxypyrrolidin-l-yl)-3,3-dimethyl-l-oxobutan-2-yl)-lH-l,2,3-triazole-4-carboxamide (Compound 16)

SMILES CC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O)n1cc(nn1)C(N)=O

InChI Key InChIKey=YDQCNPGWFYTEAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552700   

LigandPNGBDBM552700(l-((S)-l-((2S,4R)-2-(((R)-3-([l,l'-biphenyl]-4-yl)...)
Affinity DataIC50: 3.31E+3nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022103411