BDBM552694 (2S,4R)-N-((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-oxopropan-2-yl)-l-((S)-3,3-dimethyl-2-(lH-l,2,3-triazol-l-yl)butanoyl)-4-hydroxypyrrolidine-2-carboxamide (Compound 9)::WO2022103411, Example S9

SMILES CC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O)n1ccnn1

InChI Key InChIKey=SFONCPIWPDSZRH-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 552694   

LigandPNGBDBM552694((2S,4R)-N-((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-...)
Affinity DataIC50: 450nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022103411

LigandPNGBDBM552694((2S,4R)-N-((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-...)
Affinity DataKd:  260nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM552694((2S,4R)-N-((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-...)
Affinity DataKd:  170nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed