BDBM552613 WO2022101377, Example 12

SMILES Cc1nnc2CN[C@H](c3c4C[C@@H](Cc4sc3-n12)C(=O)NCc1ccc(OC(F)F)nc1)c1ccccc1Cl

InChI Key InChIKey=SORZTJFOJYFKDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552613   

TargetPlatelet-activating factor receptor(Human)
Boehringer Ingelheim International

WIPO
LigandPNGBDBM552613(WO2022101377, Example 12)
Affinity DataIC50: 1.90nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101377