BDBM552516 WO2022098809, Example 4-3::WO2022098809, Example 4-7

SMILES COc1cc2CCN(C)Cc2cc1Nc1ncc(C(N)=O)c(Nc2c(C)cccc2F)n1

InChI Key InChIKey=HTDGUKKHGDXPJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 552516   

LigandPNGBDBM552516(WO2022098809, Example 4-3 | WO2022098809, Example ...)
Affinity DataIC50: 0.260nMAssay Description: Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to colum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098809

LigandPNGBDBM552516(WO2022098809, Example 4-3 | WO2022098809, Example ...)
Affinity DataIC50: 0.300nMAssay Description: Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to colum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098809

LigandPNGBDBM552516(WO2022098809, Example 4-3 | WO2022098809, Example ...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed