BDBM552062 US11312726, Compound 33

SMILES Cc1nnc2[C@H](CC(=O)Nc3ccc4nonc4c3)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1

InChI Key InChIKey=OSSPYPVFOCWVPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552062   

TargetBromodomain-containing protein 4 [349-460](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552062(US11312726, Compound 33)
Affinity DataIC50: 19nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552062(US11312726, Compound 33)
Affinity DataIC50: 248nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent