BDBM552038 US11312726, Compound 9

SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)Nc1ccc3NC(=O)C4(CC4)c3c1)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=QJYIXOJZQVQQKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552038   

TargetBromodomain-containing protein 4 [44-167](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552038(US11312726, Compound 9)
Affinity DataIC50: 49nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552038(US11312726, Compound 9)
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent