BDBM552027 (S*)-(3-amino- 4,5- dihydropyrano[3, 4-c]pyrazol- 2(7H)-yl)(8- chloro-1,2,3,4- tetrahydro- quinolin-4- yl)methanone::US11312723, Example 202

SMILES Nc1c2CCOCc2nn1C(=O)[C@H]1CCNc2c(Cl)cccc12

InChI Key InChIKey=GTINRKKTNCYCPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552027   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM552027((S*)-(3-amino- 4,5- dihydropyrano[3, 4-c]pyrazol- ...)
Affinity DataIC50: 90nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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