BDBM552002 (S*)-(3-amino- 6-ethyl-4,5,6,7- tetrahydro- pyrazolo[3,4- c]pyridin-2- yl)(8-methyl- 1,2,3,4- tetrahydro quinolin-4- yl)methanone::US11312723, Example 173

SMILES CCN1CCc2c(C1)nn(C(=O)[C@H]1CCNc3c(C)cccc13)c2N

InChI Key InChIKey=FLGAWSGCLBFBRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552002   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM552002((S*)-(3-amino- 6-ethyl-4,5,6,7- tetrahydro- pyrazo...)
Affinity DataIC50: 20nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetProthrombin(Human)
Rockefeller University

US Patent
LigandPNGBDBM552002((S*)-(3-amino- 6-ethyl-4,5,6,7- tetrahydro- pyrazo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent