BDBM551961 (S*)-(3-amino-6- (methylsulfonyl)- 4,5,6,7- tetrahydro- pyrazolo[3,4- c]pyridin-2- yl)(2-chloro- 4,5,6,7-::US11312723, Example 131

SMILES CS(=O)(=O)N1CCc2c(C1)nn(C(=O)[C@H]1CCCc3[nH]c(Cl)cc13)c2N

InChI Key InChIKey=NXEHTAKJDKZTQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551961   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM551961((S*)-(3-amino-6- (methylsulfonyl)- 4,5,6,7- tetrah...)
Affinity DataIC50: 30nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetProthrombin(Human)
Rockefeller University

US Patent
LigandPNGBDBM551961((S*)-(3-amino-6- (methylsulfonyl)- 4,5,6,7- tetrah...)
Affinity DataIC50: 1.50E+3nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent