BDBM551921 (3-amino-5- methyl-4,5,6,7- tetrahydro- pyrazolo[4,3- c]pyridin-2- yl)(2-methyl- 1H-indol-4- yl)methanone::US11312723, Example 85

SMILES CN1CCc2nn(C(=O)c3cccc4[nH]c(C)cc34)c(N)c2C1

InChI Key InChIKey=XOWJGMYCCKCBLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551921   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM551921((3-amino-5- methyl-4,5,6,7- tetrahydro- pyrazolo[4...)
Affinity DataIC50: 30nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetProthrombin(Human)
Rockefeller University

US Patent
LigandPNGBDBM551921((3-amino-5- methyl-4,5,6,7- tetrahydro- pyrazolo[4...)
Affinity DataIC50: 6.00E+4nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent