BDBM551912 & 73: (3-amino-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl)(8-chloro-1,2,3,4-tetrahydroquinolin-4-yl)methanone::US11312723, Example 72

SMILES Nc1nn(C(=O)[C@H]2CCNc3c(Cl)cccc23)c2CNCCc12

InChI Key InChIKey=PXBXVTVZSHSDHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551912   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM551912(& 73: (3-amino-4,5,6,7-tetrahydropyrazolo[3,4-c]py...)
Affinity DataIC50: 70nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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