BDBM551905 (3-amino-6-(methylsulfonyl)-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-2-yl)(8-ethyl-1,2,3,4-tetrahydroquinolin-4-yl)methanone::US11312723, Example 65::US11312723, Example 66

SMILES CCc1cccc2C(CCNc12)C(=O)n1nc(N)c2CCN(Cc12)S(C)(=O)=O

InChI Key InChIKey=HOWHRPFUMVOEQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551905   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM551905(US11312723, Example 66 | (3-amino-6-(methylsulfony...)
Affinity DataIC50: 90nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM551905(US11312723, Example 66 | (3-amino-6-(methylsulfony...)
Affinity DataIC50: 1.00E+5nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent