BDBM551852 (3-amino-6-benzyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-2-yl)(2-methyl-1H-indol-4-yl)methanone and (3-amino-6-benzyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl)(2-methyl-1H-indol-4-yl)methanone::US11312723, Example 10

SMILES Cc1cc2c(cccc2[nH]1)C(=O)n1nc2CN(Cc3ccccc3)CCc2c1N

InChI Key InChIKey=QJMKVOPDZNNLBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551852   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM551852((3-amino-6-benzyl-4,5,6,7-tetrahydropyrazolo[3,4-c...)
Affinity DataIC50: 30nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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