BDBM551849 Tert-butyl 3-amino-2-(2-methyl-1H-indole-4-carbonyl)-4,5-dihydro-2H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate and tert-butyl 3-amino-1-(2-methyl-1H-indole-4-carbonyl)-4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate::US11312723, Example 7

SMILES Cc1cc2c(cccc2[nH]1)C(=O)n1nc2CN(CCc2c1N)C(=O)OC(C)(C)C

InChI Key InChIKey=IHLKLCIDIHLQJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551849   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandPNGBDBM551849(Tert-butyl 3-amino-2-(2-methyl-1H-indole-4-carbony...)
Affinity DataIC50: 70nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetProthrombin(Human)
Rockefeller University

US Patent
LigandPNGBDBM551849(Tert-butyl 3-amino-2-(2-methyl-1H-indole-4-carbony...)
Affinity DataIC50: 2.50E+4nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent