BDBM551745 US11312722, Compound 35

SMILES COc1ccc(Cn2nc(cc2Nc2cc(O)cc(O)c2C(=O)N2Cc3ccc(OCCN(C)C)cc3C2)-c2ccccc2)cc1

InChI Key InChIKey=LJIGUCUIUKUKIF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551745   

TargetHsp90 chaperone protein kinase-targeting subunit(Cryptococcus neoformans var. neoformans serotype D...)
Trustees of Boston University

US Patent
LigandPNGBDBM551745(US11312722, Compound 35)
Affinity DataEC50:  91nMAssay Description:EC50 values were determined by FP-based equilibrium competition assay performed in 384-well format using whole cell lysates prepared from C. neoforma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetHeat shock protein 90 homolog(Yeast)
Trustees of Boston University

US Patent
LigandPNGBDBM551745(US11312722, Compound 35)
Affinity DataEC50:  14nMAssay Description:EC50 values were determined by FP-based equilibrium competition assay performed in 384-well format using whole cell lysates prepared from C. neoforma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent