BDBM551444 7-(methoxymethyl)-2-(1-methyl-1H-pyrazol-4-yl)-9H-::US11312716, Example 50

SMILES COCc1cc2[nH]c3nc(ccc3c2cn1)-c1cnn(C)c1

InChI Key InChIKey=FPTITWBQLLNPFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551444   

TargetMicrotubule-associated protein tau(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM551444(7-(methoxymethyl)-2-(1-methyl-1H-pyrazol-4-yl)-9H-...)
Affinity DataIC50: 25.1nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent