BDBM551441 7-methyl-2-(1-methyl-1H-pyrazol-4-yl)-9H-::US11312716, Example 47

SMILES Cc1cc2[nH]c3nc(ccc3c2cn1)-c1cnn(C)c1

InChI Key InChIKey=HJTGGRQKDGBCGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551441   

TargetMicrotubule-associated protein tau(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM551441(7-methyl-2-(1-methyl-1H-pyrazol-4-yl)-9H- | US1131...)
Affinity DataIC50: 39.8nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent