BDBM551399 8-chloro-2-[(5-methylpyrazin-2-yl)methyl]-1- [(2R,4R)-2-methyltetrahydro-2H-pyran-4-yl]-1H- imidazo[4,5-c]quinoline::US11312713, Example 95A::US11312713, Example 96

SMILES C[C@@H]1C[C@@H](CCO1)n1c(Cc2cnc(C)cn2)nc2cnc3ccc(Cl)cc3c12

InChI Key InChIKey=YYSUHJMDOKKANR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 551399   

LigandPNGBDBM551399(US11312713, Example 96 | 8-chloro-2-[(5-methylpyra...)
Affinity DataIC50: 2.16nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM551399(US11312713, Example 96 | 8-chloro-2-[(5-methylpyra...)
Affinity DataIC50: 3.21nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM551399(US11312713, Example 96 | 8-chloro-2-[(5-methylpyra...)
Affinity DataIC50: 6.06nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM551399(US11312713, Example 96 | 8-chloro-2-[(5-methylpyra...)
Affinity DataIC50: 7.32nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent