BDBM551372 1-[(2R,4R)-2-methyltetrahydro-2H-pyran-4-yl]-2- (1,3-thiazol-4-ylmethyl)-8-(trifluoromethyl)-1H- imidazo[4,5-c]quinoline, formate salt::US11312713, Example 69

SMILES C[C@@H]1C[C@@H](CCO1)n1c(Cc2cscn2)nc2cnc3ccc(cc3c12)C(F)(F)F

InChI Key InChIKey=VAKSQSPOORBCAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551372   

LigandPNGBDBM551372(1-[(2R,4R)-2-methyltetrahydro-2H-pyran-4-yl]-2- (1...)
Affinity DataIC50: 3.33nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM551372(1-[(2R,4R)-2-methyltetrahydro-2H-pyran-4-yl]-2- (1...)
Affinity DataIC50: 7.39nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent