BDBM551339 2-[(4-methoxy-1H-pyrazol-1-yl)methyl]-1-[(3R)-1- methylpyrrolidin-3-yl]-1H-imidazo[4,5-c] quinoline-8-carbonitrile, formate salt::US11312713, Example 36

SMILES COc1cnn(Cc2nc3cnc4ccc(cc4c3n2[C@@H]2CCN(C)C2)C#N)c1

InChI Key InChIKey=VKBQZVKBWYNNAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551339   

LigandPNGBDBM551339(2-[(4-methoxy-1H-pyrazol-1-yl)methyl]-1-[(3R)-1- m...)
Affinity DataIC50: 4.63nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM551339(2-[(4-methoxy-1H-pyrazol-1-yl)methyl]-1-[(3R)-1- m...)
Affinity DataIC50: 5nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent