BDBM551337 1-[(3R)-1-methylpyrrolidin-3-yl]-2-[(5-methyl-2H- tetrazol-2-yl)methyl]-1H-imidazo[4,5-c]quinoline- 8-carbonitrile, formate salt::US11312713, Example 34

SMILES CN1CC[C@H](C1)n1c(Cn2nnc(C)n2)nc2cnc3ccc(cc3c12)C#N

InChI Key InChIKey=CVIKJUDYOSLROL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551337   

LigandPNGBDBM551337(1-[(3R)-1-methylpyrrolidin-3-yl]-2-[(5-methyl-2H- ...)
Affinity DataIC50: 5.04nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM551337(1-[(3R)-1-methylpyrrolidin-3-yl]-2-[(5-methyl-2H- ...)
Affinity DataIC50: 5.53nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent