BDBM551335 1-(4,4-difluoro-1-methylpyrrolidin-3-yl)-2-[(5- methyl-1,2,4-oxadiazol-3-yl)methyl]-1H- imidazo[4,5-c]quinoline-8-carbonitrile, ENT 1::US11312713, Example 32

SMILES CN1CC(n2c(Cc3noc(C)n3)nc3cnc4ccc(cc4c23)C#N)C(F)(F)C1

InChI Key InChIKey=UEOIDXNOHZNZQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551335   

LigandPNGBDBM551335(1-(4,4-difluoro-1-methylpyrrolidin-3-yl)-2-[(5- me...)
Affinity DataIC50: 4.59nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM551335(1-(4,4-difluoro-1-methylpyrrolidin-3-yl)-2-[(5- me...)
Affinity DataIC50: 5.98nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent