BDBM551143 (*S)-2-(1-Fluoroethyl)-3-(7-methyl-1H-indazol-5-yl)-5-::US11312712, Example 257

SMILES C[C@H](F)c1nc2ccc(nc2n1-c1cc(C)c2[nH]ncc2c1)C(F)(F)F

InChI Key InChIKey=SHLJMZQKGXFFPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551143   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM551143((*S)-2-(1-Fluoroethyl)-3-(7-methyl-1H-indazol-5-yl...)
Affinity DataIC50: 0.0500nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent