BDBM55084 N-[4-[(2-chlorobenzoyl)amino]-3-fluoro-phenyl]picolinamide::N-[4-[(2-chlorobenzoyl)amino]-3-fluorophenyl]pyridine-2-carboxamide::N-[4-[(2-chlorophenyl)carbonylamino]-3-fluoranyl-phenyl]pyridine-2-carboxamide::N-[4-[[(2-chlorophenyl)-oxomethyl]amino]-3-fluorophenyl]-2-pyridinecarboxamide::VU0362060-1::cid_46869942

SMILES Fc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl

InChI Key InChIKey=NYDUFWZZLKDRLO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 55084   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55084(N-[4-[(2-chlorophenyl)carbonylamino]-3-fluoranyl-p...)
Affinity DataEC50:  480nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55084(N-[4-[(2-chlorophenyl)carbonylamino]-3-fluoranyl-p...)
Affinity DataEC50:  740nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55084(N-[4-[(2-chlorophenyl)carbonylamino]-3-fluoranyl-p...)
Affinity DataEC50:  556nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55084(N-[4-[(2-chlorophenyl)carbonylamino]-3-fluoranyl-p...)
Affinity DataEC50:  739nMAssay Description:Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed