BDBM550837 1-{1-(Cyclohexylmethyl)-5-[(2,5-difluorobenzyl)oxy]-4-fluoro-1H-pyrazol-3-yl}-N-methylmethanamine Hydrochloride::US11312688, Example 351::US11576897, Example 351
SMILES CNCc1nn(CC2CCCCC2)c(OCc2cc(F)ccc2F)c1F
InChI Key InChIKey=GQHSWEDTHMXRID-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 550837
Affinity DataKi: 0.980nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:Specifically, a solution containing 50 μL of [3H]-citalopram (GE Healthcare) diluted with SERT buffer (50 mmol/L Tris-HCl (pH=7.4) containing 12...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:5-HT2A: A solution containing 50 μL of [H]-ketanserin (the final concentration: 1 nM), 2 μL of a solution of a test compound in DMSO or a s...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:5-HT2C: A solution containing 50 μL of [H]-mesulergine (GE Healthcare) diluted with 50 mmol/L Tris-HCl (pH=7.4) (the final concentration: about ...More data for this Ligand-Target Pair