BDBM550533 US11311520, Example 27::tert-Butyl [1-({4-[(8′-methyl-1′,5′-dioxo-1′,5′-dihydro-2′H-spiro[cyclohexane-1,3′-imidazo[1,5-a]pyridin]-6′-yl)amino]thieno[2,3-d]pyrimidin-6-yl}carbonyl)azetidin-3-yl]carbamate

SMILES Cc1cc(Nc2ncnc3sc(cc23)C(=O)N2CC(C2)NC(=O)OC(C)(C)C)c(=O)n2c1C(=O)NC21CCCCC1

InChI Key InChIKey=BHDIJUOTDNAIJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550533   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM550533(tert-Butyl [1-({4-[(8′-methyl-1′,5R...)
Affinity DataIC50: 4nMAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
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Date in BDB:
8/6/2022
Entry Details
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