BDBM550502 US11306105, Compound 206

SMILES Cc1nnc2[C@H](CC(=O)NCCO)N=C(c3c(C)c(CC#N)sc3-n12)c1ccc(Cl)cc1

InChI Key InChIKey=MVMMNLALSKWQDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 550502   

TargetBromodomain testis-specific protein [22-138](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550502(US11306105, Compound 206)
Affinity DataIC50: 642nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550502(US11306105, Compound 206)
Affinity DataIC50: 197nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2022
Entry Details
Go to US Patent