BDBM550499 US11306105, Compound 203

SMILES CN1CCN(CCCNC(=O)C[C@@H]2N=C(c3c(C)c(CC#N)sc3-n3c(C)nnc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=OWEUSZMQBNFEOO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550499   

TargetBromodomain-containing protein 4 [44-167](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550499(US11306105, Compound 203)
Affinity DataIC50: 134nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2022
Entry Details
Go to US Patent