BDBM550330 US11306081, Example 178

SMILES CC(C)(O)COc1ccc2nc(NC(=O)Cc3ccc(Oc4ncccc4C(N)=O)c(F)c3)n(CC3CC3)c2c1

InChI Key InChIKey=HRQCCCNAAGFBIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550330   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550330(US11306081, Example 178)
Affinity DataIC50: 14nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent