BDBM549562 US11306075, Ex. 6::US20240158379, Example 6

SMILES CC(=O)CCc1oc2ccc(cc2c1-c1ccc(C)o1)-c1ccncc1

InChI Key InChIKey=JJPCPBRFIXIIFI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549562   

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM549562(US11306075, Ex. 6 | US20240158379, Example 6)
Affinity DataIC50: 6.35E+3nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM549562(US11306075, Ex. 6 | US20240158379, Example 6)
Affinity DataIC50: 6.35E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
Go to US Patent