BDBM549550 US11306071, Compound 125::US11306071, Compound 128

SMILES C[C@H](NC(=O)c1nc(-c2ccc3ncccc3c2)c(nc1N)-c1ccccc1)c1ncccn1

InChI Key InChIKey=SUMMROKUOAWMOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549550   

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549550(US11306071, Compound 125 | US11306071, Compound 12...)
Affinity DataIC50: 1.20nMAssay Description:The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549550(US11306071, Compound 125 | US11306071, Compound 12...)
Affinity DataIC50: 2nMAssay Description:The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent