BDBM549544 US11306071, Compound 119

SMILES C[C@H](NC(=O)c1nc(-c2ccc3[nH]ncc3c2)c(nc1N)-c1ccn(C)n1)c1cccc(n1)C#N

InChI Key InChIKey=VFAZUFKRAKNYAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549544   

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549544(US11306071, Compound 119)
Affinity DataIC50: 12nMAssay Description:The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent