BDBM549542 US11306071, Compound 117::US11306071, Compound 118

SMILES C[C@H](NC(=O)c1nc(-c2ccc3ncccc3c2)c(nc1N)-c1cccc(c1)C#N)c1cccc(n1)C#N

InChI Key InChIKey=FONHMBCXXCUTIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549542   

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549542(US11306071, Compound 117 | US11306071, Compound 11...)
Affinity DataIC50: 269nMAssay Description:The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549542(US11306071, Compound 117 | US11306071, Compound 11...)
Affinity DataIC50: 16nMAssay Description:The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent